Toon Disney (see also Jetix)
(launched in 1998; replaced by Disney XD in 2009)
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This was mostly reruns from other networks, but there were a few things that aired here first (at least in the US).

The Weekenders (10/19/2003 - 2/29/2004; s1-2 aired on ABC, s3 on UPN)
Fillmore! (1/2/2004 - 1/30/2004; s1-s2e21 aired on ABC)
Super Robot Monkey Team Hyperforce Go! (9/18/2004 - 12/16/2006)
W.I.T.C.H. (9/18/2004 - 12/23/2005; also aired on France 3)
Oban Star-Racers (6/5/2006 - 12/11/2006; originally on France 3 and Toon Disney Japan)
Pucca (9/18/2006 - 8/11/2008; originally on MBC in South Korea)
Cars Toons (10/27/2008 - 10/29/2008; later episodes aired on Disney Channel)